AGE REVERSAL WITH
GHK-Cu Copper Peptide
The human peptide GHK (glycyl-l-histidyl-l-lysine) has multiple biological actions, all of which, according to our current knowledge, appear to be health positive.
Content courtesy: reverseagingwithghk.com
Skin & Hair
GHK was first studied for wound healing (1983+) and later for its effects on skin and hair. In many controlled, peer-reviewed published articles, GHK was found to:
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Tightened and Loose Skinand thicken older skin.
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Repairedprotective skin barrier proteins.
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Improvedskin firmness, elasticity, and clarity.
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Reduced fine linesdepth of wrinkles, and overall appearance.
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Reduced fine linesdepth of wrinkles, and overall appearance.
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Smoothedrough skin.
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Reduced Photodamagemottled hyperpigmentation, skin spots and lesions.
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Improvedoverall appearance.
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Protected skin cellsfrom UV radiation.
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Increased Hair Growthand thickness, enlarge hair follicle size.
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Accelerated Wound Healingbut better when used in liposomes due to its sensitivity to carboxypeptidase breakdown effects.
Anti-Cancer Actions
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Topped 1,309 bioactive compoundsas the Broad Institute computer recommended molecule for the treatment of human METASTATIC COLON CANCER
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GHK, at 1 nanomolarreset the PROGRAMMED CELL DEATH system in human cancer cells (human neuroblastoma, leukemia, and breast cancer) but did not affect healthy cells.
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GHK-copper plusascorbic acid suppressed a sarcoma in mice.
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GHK inhibited NFKB p65which is believed to promote cancer growth.
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Repaired Damaged DNAat cellular level at 1 nanomolar (47 genes up, 5 genes down).
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GHK-copperinduced cell differentiation.
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Reset 84 genesto growth inhibition or cancer inhibition.
Lung Protection
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Topped 1,309 bioactive compoundsas Broad Institute computer recommended molecule for treatment of chronic obstructive obstructive pulmonary disease. Restored healthy function in COPD affected cells at 10 nanomolar.
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Protected Lung Cellsfrom damage by both bleomycin and lipopolysaccharide-induced injury.
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In fetal lung cellsGHK-Cu (at concentrations of 0.1, 1.0, and 10 nanomolar) produced dose-response changes in 329 human fetal lung genes of the extracellular matrix.
Antioxidant / Anti-Inflammatory
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Increased SOD1 ActivitySuppressed toxic products of lipid oxidation alpha,beta-4-hydroxy-trans-2-noneal and acrolein, peroxyl radicals, hydroxyl radicals, p38 MAPK, IL-6, IL-17, TNF alpha, and strongly suppressed NFKB, a molecule which is believed to be a primary cause of many diseases of aging.
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Completely Blocked CU2+ Oxidationof low density lipoproteins while SOD1 gave only 20% blocking.
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Blocked Release ofOxidizing iron from ferritin.
Brain & Nerves
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Altered expression of human genesimportant in neuron function by 50%, plus or minus, with 408 UP and 230 DOWN.
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Induced strong Anti-Anxiety & Anti-Aggressioneffects in rats within 12 minutes at a weight equivalent of 35 micrograms in 70 Kg humans.
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Induced Anti-Pain Activityin rats within 12 minutes.
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Alleviated neuronal apoptosisdue to Intracerebral hemorrhage.
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Now used clinically in humansfor the treatment of damaged spinal segments in the neck. Treatment was for 20 days with a daily injection of 0.25 mg GHK-Cu into the skin around the damaged area. The cost of GHK-Cu is about $0.01 a milligram.
Stem Cells & OTher Actions
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Caused adult MCS Stem Cellsto produce more growth factors, increased stem cell differentiation.
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Enhanced activity ofalginate hydrogels for human cord blood MCS Stem Cell Ostegenesis.
ADDITIONAL ACTIONS OF GHK
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Increased the healing ofmany tissues including skin, stomach, intestine lining, bone tissue.
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Strongly chemo-attractedcapillary cells, mast cells, and macrophages.
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Strongly activated genes ofthe Ubiquitin proteasome system used for cell cleansing. (41 genes up, 1 gene down).
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Blocked Locked Cortisone'santi-regeneration effects.
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Suppressed the Insulinand insulin-like system that reduces lifespan in roundworms.
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Reduced Fibrinogen synthesisFibrinogen levels are the top predictor of cardiovascular heart disease.
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Increased Myostatingene expression 9.4 fold. Myostatin inhibits heart failure.